COST Programme

See list of posters.

Electronic version of conference programme (iCalendar format):

Friday, 19th April 2013

10:00 — 19:00 Registration

OREA Hotel Pyramida, Prague, Reception Foyer

14:00 — 14:30 Opening, organizational information and information from COST
Bruce Turnbull & Vladimír Křen & Ladislav Petruš
Chairperson: Bruce Turnbull, UK
14:30 — 15:10 Development of new biocatalysts for the synthesis of rare furanosides
Richard Daniellou & Vincent Ferrieres, France

Keynote lecture

15:10 — 15:30 Differences in the mesoscopic structures of complex coacervates of proteins with flexible and stiff polyelectrolytes
A. Basak Kayitmazer, Turkey
SESSION 1 Conference Room III

Enzymatic methods in glycobiology

Chairperson: Maurice Franssen, Netherlands
15:30 — 15:50 Enzyme cascades for the synthesis of multimeric recognition motifs: From fluorescent labeling to runaway block polymerization
Wolf-Dieter Fessner, Germany
15:50 — 16:10 Diglycosidases: a promising tool for the synthesis of tailored bioactive compounds
Javier D. Breccia, Argentina
16:10 — 16:30 UDP-sulfoquinovose synthase from the hyperthermoacidophilic archaeon Sulfolobus acidocaldarius
Behnam Zolghadr, Austria
16:30 — 17:00 Coffee Break

Hotel Restaurant

SESSION 2 Conference Room III

Carbohydrate synthesis and multivalency

Chairperson: Stefan Oscarson, Ireland
17:00 — 17:20 Synthesis and conjugation of multiantennary N-glycan azides
Carlo Unverzagt, Germany
17:20 — 17:40 C-Glycoside functionalized multivalent ligands as potent inhibitors of DC-SIGN lectin
Jitka Moravcová, Czech Republic
17:40 — 18:00 Photosensitive multivalent glycomimetics
Thisbe K. Lindhorst, Germany
18:00 — 18:20 Immunostimulatory glycoclusters derived from β-(1→2)-linked oligomannosides: Recent progress from in vitro and in vivo studies
Reko Leino, Finland
18:20 — 18:40 Studying the structure of peptide dendrimers by molecular dynamics simulations: branch length, charge, pH and glycosylation
Antonio M. Baptista, Portugal
18:40 — 19:30 Poster Session 1

all posters will be displayed

19:30 — 23:59 Core Group meeting TBA

Saturday, 20th April 2013

09:00 — 18:00 Registration

OREA Hotel Pyramida, Prague, Reception Foyer

SESSION 3 Conference Room III

Carbohydrate-protein interactions

Chairperson: Lothar Elling, Germany
09:00 — 09:40 Siglec ligand decorated nanoparticles for in vivo targeting of immune cells
James C. Paulson, USA

Keynote Lecture

09:40 — 10:00 Influence of lectin valency on surface avidity and glycolipid dynamics in membranes
Anne Imberty, France
10:00 — 10:20 Tetravalent glycocylopeptide with nanomolar affinity to wheat germ agglutinin
Michele Fiore, France
10:20 — 10:40 Langerin, a C-type lectin from dendritic cells, can switch from a Ca2+-dependent to a Ca2+-independent binding mode as a function of the glycans
Franck Fieschi, France
10:40 — 11:20 Coffee Break

Hotel Restaurant

SESSION 4 Conference Room III

Carbohydrate-nucleic acids interactions; Materials

Chairperson: Jean-Louis Reymond, Switzerland
11:20 — 11:40 Sugar-oligoamides: Chemical tools to study carbohydrate- and glycoprotein-DNA recognition
Cristina Vicent, Spain
11:40 — 12:00 Glycotargeted gene delivery with cyclodextrins: Making bridges between nucleic acids and lectins
José M. García Fernández, Spain
12:00 — 12:20 Potent divalent inhibitors containing rigid spacer units
Roland J. Pieters, Netherlands
12:20 — 12:40 Materials for Glycomics and as Glycomimetics
Matthew I. Gibson, UK
12:40 — 13:00 Carbohydrate-decorated nanodiamonds for effective sensing and disruption of bacterial and lectin-mediated interactions with glycans
Aloysius Siriwardena, France
13:00 — 14:00 Lunch

Hotel Restaurant

14:00 — 15:00 Poster Session 2

All posters will be displayed.

Coffee and drinks will be served.

SESSION 5 Conference Room III

Glycomaterials in the medicinal applications

Chairperson: Roland Pieters, Netherlands
15:00 — 15:20 Adhesion-targeted therapies in cancer: Modulation of melanoma cells motility and adhesion induced by carbohydrate-based multivalent scaffolds
Barbara Richichi, Italy
15:20 — 15:40 Sortase-mediated modification of carbohydrate binding proteins for drug delivery
Daniel J. Williamson, UK
15:40 — 16:00 Facile approach towards synthetic glycolipids: Potential as soft materials and antimicrobial agents
Velasco-Torrijos Trinidad, Ireland
16:00 — 16:20 New tools for deciphering plant-microbe interactions involving lipochitin oligosaccharides
Mikkel B. Thygesen, Denmark
16:20 — 16:40 Immunomodulating properties of TLR4-active cationic and anionic amphiphiles
Francesco Peri, Italy
16:40 — 17:00 Coffee Break

Congress Hall Foyer

SESSION 6 Conference Room III

Carbohydrate structures and multivalency

Chairperson: Cristina Nativi, Italy
17:00 — 17:20 Synthesis of Lewis b-containing glycoconjugates for investigations of Helicobacter pylori binding to human glycan receptor structures
Martina Lahmann & Stefan Oscarson, UK & Ireland
17:20 — 17:40 Glycofullerenes as antiadhesive molecules and glycosyltransferase inhibitors
Stéphane P. Vincent, Belgium
17:40 — 18:00 Imaging cell surface glycosylation in vivo using bioorthogonal ‘double-click’ chemistry
Yelena Wainman, UK
18:00 — 18:20 Bovine submaxillary mucin (BSM) films: Interaction with lectins and unique non-fouling properties
Seunghwan Lee, Denmark
20:00 — 23:59 Social Dinner

Restaurant Senses, Hotel Prague Castle Lindner

(ca 10 min walk, 550 m)

Sunday, 21st April 2013

SESSION 7 Conference Room III

Carbohydrates and multivalency

Chairperson: Olivier Renaudet, France
09:00 — 09:20 Incorporation of a calixarene-based glucose functionalised bolaamphiphile in lipid bilayers for multivalent lectin recognition
Francesco Sansone, Italy
09:20 — 09:40 Impact of the S-Layer and its glycosylation status on the attachment to a surface and the subsequent biofilm formation of Tannerella forsythia
Andrea Koerdt, Austria
09:40 — 10:00 pH dependent conformational study of a synthetic receptor for molecular recognition of carbohydrates
Miguel Machuqueiro, Portugal
10:00 — 11:00 Management Committee Meeting
11:00 — 12:00 Meetings of the Working groups